ABSTRACT
ABSTRACT: In an attempt to protect the high-risk demographic and reduce burden on health care systems, concomitant administration of COVID-19 and influenza vaccines has been recommended by health bodies. The ComFluCOV trial indicates this is well tolerated with no reduction in immune response to either vaccine. A 48-year-old woman with right oropharyngeal squamous cell carcinoma underwent postradiotherapy FDG PET/CT, which demonstrated complete metabolic response. Incidental avid bilateral axillary lymphadenopathy of benign configuration was noted and concluded to be reactive in response to recent Pfizer-BioNTech booster and influenza vaccination. This is expected to be seen more frequently over the coming months.
Subject(s)
COVID-19 , Influenza, Human , COVID-19/prevention & control , Female , Fluorodeoxyglucose F18/metabolism , Humans , Influenza, Human/metabolism , Influenza, Human/pathology , Influenza, Human/prevention & control , Lymph Nodes/pathology , Middle Aged , Positron Emission Tomography Computed Tomography , Seasons , VaccinationABSTRACT
ABSTRACT: A 46-year-old woman with previous history of breast cancer had follow-up 18F-FDG PET/CT 5 days after COVID-19 vaccination. In addition to avid axillary nodes, a well-documented feature, the scan demonstrated diffuse splenic and marrow uptake. Clinical history, laboratory, and scan findings were in keeping with SIRS (systemic inflammatory response). The patient recovered with supportive management. On follow-up, 18F-FDG PET/CT imaging 3 months later features had resolved. SIRS after vaccination may be observed on 18F-FDG PET/CT.
Subject(s)
COVID-19 , Fluorodeoxyglucose F18 , COVID-19 Vaccines , Female , Follow-Up Studies , Humans , Immunity , Middle Aged , Positron Emission Tomography Computed Tomography , Positron-Emission Tomography , SARS-CoV-2 , VaccinationABSTRACT
ABSTRACT: A 70-year-old man with newly diagnosed prostate cancer underwent 18F-PSMA-1007 PET/CT for staging. PSMA-avid primary prostatic malignancy was identified. Incidental intense patchy peripheral lung uptake was also noted. The patient tested positive for COVID-19 infection.
Subject(s)
COVID-19 , Prostatic Neoplasms , Aged , Edetic Acid , Humans , Lung/pathology , Male , Neoplasm Staging , Niacinamide/analogs & derivatives , Oligopeptides , Positron Emission Tomography Computed Tomography , Prostatic Neoplasms/diagnostic imaging , Prostatic Neoplasms/pathology , SARS-CoV-2ABSTRACT
ABSTRACT: The rapid rollout of COVID-19 vaccination is accompanied by incidental findings on 18F-FDG PET/CT. Most cases describe reactive axillary lymphadenopathy. A 46-year-old woman with previous history of stage 3A breast cancer underwent follow-up 18F-FDG PET/CT, which demonstrated avid left axillary nodes and intense diffuse splenic uptake and moderate diffuse bone marrow uptake. She had been administered COVID-19 vaccination in the left deltoid 1 week earlier and required hospitalization for 24 hours due to fever. Symptoms settled with supportive treatment. One month after the PET/CT scan, she remained well. Sites of uptake were taken to relate to a systemic immune response.
Subject(s)
COVID-19 , Positron Emission Tomography Computed Tomography , COVID-19 Vaccines , Female , Fluorodeoxyglucose F18 , Humans , Immunity , Middle Aged , SARS-CoV-2 , VaccinationABSTRACT
ABSTRACT: World-wide mass COVID-19 vaccination has been deployed starting with those most vulnerable, including the elderly and cancer patients. A 70-year-old man with right lung cancer underwent staging FDG PET/CT, which demonstrated an avid right lung mass with avid hilar and mediastinal nodes. Avid left axillary nodes of benign configuration were also noted. The patient had the Oxford-AstraZeneca COVID-19 vaccination in the left arm a week earlier. On reflection, the axillary nodes were concluded to be reactive related to this. This is a potential COVID-19 vaccination associated pitfall on PET/CT that should be considered when interpreting FDG PET/CT images.
Subject(s)
COVID-19 , Positron Emission Tomography Computed Tomography , Aged , COVID-19 Vaccines , Fluorodeoxyglucose F18 , Humans , Lymph Nodes/diagnostic imaging , Male , Neoplasm Staging , SARS-CoV-2 , VaccinationABSTRACT
ABSTRACT: In accordance with published international COVID-19 pandemic guidance (American College of Nuclear Medicine, British Nuclear Medicine Society, and European Association of Nuclear Medicine), the use of face masks has become an essential part of infection control for both patients and staff. A 56-year-old man with mantle cell lymphoma underwent staging FDG PET/CT, which demonstrated avid lymphadenopathy below the diaphragm and an unusual diffuse FDG uptake projected over the face, raising the suspicion of cutaneous lymphomatous involvement. On reflection of the clinical scenario and scanning conditions, cutaneous involvement was discounted; the pattern of uptake and lack of CT correlate were supportive of a cutaneous artifact related to the presence of the patient's mask.